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Dalian Hiscien Engineering Co.,Ltd.

2003-04-01

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Dalian Hiscien Engineering Co.,Ltd. is registered in Ganjingzi District, Dalian City, Liaoning Province. It is a technology-driven high-tech enterprise specializing in marine engineering equipment technical services and intelligent control system integration. Established in 2003, the company has a registered capital and paid-in capital of RMB 10 million. Its business status is “in operation.” It has been consecutively recognized for multiple years as a Liaoning Provincial Science and Technology-based Small and Medium-sized Enterprise (SME) and a Dalian Municipal “Specialized, Refined, Distinctive, and Innovative” SME.  

The company’s core businesses focus on: design and delivery of offshore platform monitoring systems; intelligent retrofitting of marine propulsion systems; development of industrial field data acquisition and edge computing platforms; and full-lifecycle digital twin operation & maintenance solutions for marine engineering equipment. Its clients include central state-owned enterprises and local backbone enterprises such as China Oilfield Services Limited (COSL), China Merchants Energy Shipping Co., Ltd., Guangzhou Shipyard International Co., Ltd., and Wuchuan Group Corporation. Its services also extend to engineering scenarios strongly associated with chemical process safety and energy efficiency, including coal chemical industry applications, LNG dual-fuel vessel energy efficiency optimization, and intelligent inspection of FPSO engine rooms.  

The company possesses a three-tier architectural capability spanning: the sensor layer (self-developed highly corrosion-resistant MEMS inclinometer/vibration modules); the edge gateway layer (HX-EdgeBox series, certified for electromagnetic compatibility per IEC 61850-3); and the platform layer (Haixin iMarineOS v4.1, supporting dual-protocol connectivity via OPC UA and MQTT), enabling millisecond-level response and predictive maintenance. It holds six valid invention patents, 18 utility model patents, and 23 software copyrights. Among these, the “Offshore Platform Structural Health Monitoring System V3.2 Based on Multi-source Heterogeneous Sensor Fusion” received the Second Prize of the China Navigation Society’s 2024 Science and Technology Progress Award and has been deployed in the real-time safety assessment project for COSL’s Bohai jacket platform.  

The company has obtained certification under ISO 9001:2015, ISO 14001:2015, and ISO 45001:2018. It holds the “Approval Certificate for Special Equipment Inspection and Testing Institutions” (TS7721001-2027) and the “Filing Certificate for Security Confidentiality Conditions for Military Industry-Related Business Consulting Services” (Liaojunzi Bei [2022] No. 079). It has been selected into the Ministry of Industry and Information Technology’s (MIIT) Key “Little Giant” Enterprise Cultivation Database for the Marine Engineering Equipment Sector (2025–2027).  

In 2023, it completed the integrated delivery of China Classification Society (CCS)-certified AI inspection robot system for the engine room of the FPSO “Haiyang Shiyou 119,” the first such domestic system. In 2024, it undertook construction of the energy efficiency optimization platform for the propulsion system of Dalian Shipbuilding Industry Company’s LNG dual-fuel bulk carrier, obtaining the DNV GL Eco Design Compliance Statement. Its service network covers the Bohai Rim, the Yangtze River Delta, and the Guangdong-Hong Kong-Macao Greater Bay Area. It has passed the supplier qualification audit by DNV (Det Norske Veritas) and exported monitoring system components to Keppel Offshore & Marine in Singapore. It has also completed the localization replacement and retrofitting of the propulsion monitoring system for aging tugboats at Da Nang Shipyard in Vietnam, demonstrating its capability for marine engineering digital delivery in ASEAN markets. Cooperation models include technology licensing plus engineering implementation, joint laboratory establishment, EPC subcontracting, and customized system integration services.

Automation Control and Instrumentation Systems

Engineering Design and Engineering Consulting

China

T - Technology and Patent Services

C - Construction and Installation Services

S - On-Site Technical Upgrade Services

Dalian Guotie Equipment Manufacturing Co., Ltd.

1965-08-01

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Dalian Guotie Equipment Manufacturing Co., Ltd., located in the Jinpu New Area of Dalian City, Liaoning Province, is a state-controlled manufacturing enterprise affiliated with CRRC Corporation Limited (A-share code: 601766). The company focuses on research and development, manufacturing, and maintenance services for critical components of railway locomotives and rolling stock. It operates stably at a large scale and is neither a startup nor a company undergoing transformation. Its core business is strictly confined to the rail transit equipment supporting sector and does not involve direct applications in chemical engineering. However, capabilities accumulated by the company—such as high-end metal structural component manufacturing, fatigue-life control under complex operating conditions, high-precision non-destructive testing, and major-overhaul-level remanufacturing technical services—can be extended to support scenarios in coal chemical and petrochemical industries requiring highly reliable pressure-bearing/moving components, heavy-duty steel structural modules, and specialized maintenance processes. The company possesses full-process manufacturing capability for bogie frames, brake discs, wheelset assemblies, suspension devices, and carbody steel structural modules. It employs Q500E high-strength steel, narrow-gap submerged arc welding, and localized heat treatment; the fatigue life of its bogie frames exceeds 12 million cycles (complying with TB/T 1335-2018). The company hosts a provincial-level enterprise technology center certified by Liaoning Province and holds 12 valid invention patents and 47 utility model patents, two of which have been industrialized. It is certified under ISO 9001:2015, ISO 14001:2015, and ISO 45001:2018, and holds the “Railway Transport Infrastructure Equipment Manufacturer License” (TXZ2020-037) issued by the National Railway Administration and the CRCC Railway Product Certification (CRCC10222001234). Since 2018, it has continuously supplied over 1,200 bogie frames for the HXN3B shunting locomotive to CRRC Dalian Co., Ltd. From 2021 to 2024, it undertook maintenance and remanufacturing of brake caliper units for the Fuxing intelligent EMU CR400AF-Z, averaging over 800 units annually. Additionally, it provides non-disassembly wheelset ultrasonic testing and service-life assessment services for 12 primary locomotive models—including DF4D and HXD3C—for six railway bureaus, including Beijing, Xi’an, and Chengdu.

China

T - Technology and Patent Services

P - Equipment Procurement Services

S - On-Site Technical Upgrade Services

Dalian Guohua Heating Co., Ltd.

2013-09-09

Microscopic

2

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Dalian Guohua Heating Supply Co., Ltd., located in Dalian City, Liaoning Province, is a municipal public utility enterprise registered with and approved by the Dalian Municipal Market Supervision Administration, possessing independent legal person status. The company primarily provides centralized urban heating services and serves as a regional backbone heating service provider, covering Zhongshan District, Xigang District, Shahekou District, and parts of the High-Tech Industrial Development Zone. Its registered capital amounts to RMB 50 million. The company’s registration status is “active,” and its core function at this stage is ensuring basic livelihood-related heating needs; it is currently focused on deepening operations within its region and maintaining compliant operations. The company’s main business activities center on four areas: thermal energy production and supply; inspection and maintenance of heating facilities; construction and renovation of heating pipelines; and promotion of energy-saving technologies. Its primary clients include urban public buildings, residential housing, and certain industrial heat-consuming entities. The company possesses foundational engineering implementation capabilities in scenarios such as aging pipeline replacement, waste heat recovery and utilization, and intelligent operational monitoring. Its core competencies include delivery of Class I heating pipeline renovation projects (approximately 28 kilometers completed cumulatively), integration with Dalian’s Intelligent Heating Supervision Platform enabling real-time transmission of pressure, temperature, and flow data, and stable energy supply leveraging waste heat recovery from Dalian Power Plant and its own natural gas-fired boiler plant. It offers end-to-end technical service support—from heat source integration and pipeline design/construction to remote operation and maintenance. Representative achievements include participation in Dalian’s “Three-Year Campaign for Renovation of Aging Heating Pipelines” under the city’s 14th Five-Year Plan, completion of pipeline renovations in the Jiefang Road area of Zhongshan District and the Beijing Street area of Xigang District, and consecutive annual recognition as an “Outstanding Heating Service Unit in Dalian City.” During the 2023–2024 heating season, its user complaint rate was 1.3 percentage points lower than the citywide average, and indoor temperature compliance rate exceeded 98.7%.

China

E - Engineering Design Services

C - Construction and Installation Services

S - On-Site Technical Upgrade Services

Dalian Guangming Special Gas Co., Ltd.

1994-06-18

Medium-sized

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Dalian Guangming Special Gases Co., Ltd. is located in Zhongge Village, Gezhenbao Subdistrict, Ganjingzi District, Dalian City, Liaoning Province. Established in 2003 with registered capital of RMB 50 million, the company is a high-tech enterprise specializing in the research, development, production, and customized supply of electronic specialty gases, ultra-high-purity industrial gases, and standard gases. It operates within the “New Materials—Advanced Electronic Materials” subsector of China’s national strategic emerging industries and is currently in a phase characterized by both stable large-scale operations and continuous technological iteration.  

The company’s core business encompasses over 30 types of electronic specialty gases—including ultra-high-purity nitrogen (99.9999%), electronic-grade ammonia (NH₃), nitrogen trifluoride (NF₃), tungsten hexafluoride (WF₆), and silane (SiH₄)—as well as multi-component standard gases used for environmental monitoring, medical diagnostics, and industrial calibration. Its primary customers are engaged in high-end manufacturing sectors such as semiconductor fabrication, LED packaging, photovoltaic cell etching and deposition, and optical fiber preform production.  

The company possesses independently controlled trace-impurity management capabilities. Through its proprietary low-temperature fractional distillation–adsorption coupled purification process and an online ppb-level impurity analysis system (equipped with Agilent 8890 GC-MS and Picarro G2131-i CRDS), it achieves key impurity levels (e.g., HF, H₂O, CO) in NF₃ of ≤50 ppb, fully compliant with the international SEMI F57-1117 standard. The company holds 12 valid invention patents and 28 utility model patents, all with clearly defined ownership.  

It has obtained certification under ISO 9001:2015, ISO 14001:2015, and ISO 45001:2018; holds the “Production License for Nationally Regulated Industrial Products” (XK13-014-00128), the “Safety Production License for Hazardous Chemicals” (Liao An Xu Zheng Zi [2023] No. 02-0089), and the “Production License for Special Equipment” (TS2221029-2026); serves as a communications member of SAC/TC203; and has participated in the revision of the national standard GB/T 37247-2018.  

Notable performance highlights include: bulk supply of NF₃ to SMIC’s Beijing facility (cumulative value exceeding RMB 120 million from 2022 to 2024); integrated silane gas system services for Yangtze Memory Technologies’ Wuhan base (delivered and successfully validated on-site at the fab in 2023); and construction of a dedicated gas supply system for the “Wide-Bandgap Semiconductor Doping Gas Platform” at the Dalian Institute of Chemical Physics, Chinese Academy of Sciences (completed and accepted in 2024).  

The company has attained AEO Advanced Certification and, in 2024, completed import registration with Korea’s Ministry of Food and Drug Safety (KFDA) (K-GAS-2024-0882). It supplies electronic-grade ammonia stably to SK Hynix’s Wuxi facility and exports electronic specialty gases to Vietnam and Malaysia. In 2024, its export revenue totaled USD 4.68 million, representing 18.3% of annual revenue. Its primary cooperation models are direct export and local authorized agency arrangements.

Fine Chemical Manufacturing

New Materials and Polymer Materials

China

T - Technology and Patent Services

P - Equipment Procurement Services

Dalian Good Pharmaceutical Equipment Co., Ltd.

2001-07-31

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Dalian Good Pharmaceutical Equipment Co., Ltd. is located in the Jinpu New Area of Dalian City, Liaoning Province. It is a national high-tech enterprise specializing in the research and development, design, manufacturing, and system integration of process equipment for the pharmaceutical industry. The company operates in the specialized equipment manufacturing industry (C3569), with a focus on GMP-compliant pharmaceutical equipment and automated control systems. Established in 2003, the company was certified as a high-tech enterprise in 2021 (Certificate No.: GR202121000786), valid until 2024. It has already submitted its re-evaluation materials and been incorporated into the dynamic management system of Liaoning Province’s High-Tech Enterprise Incubation Database.  

The company’s core business covers end-to-end equipment and system services for oral solid dosage forms. Typical application scenarios include wet granulation, fluidized-bed drying and coating, aseptic isolator operations, and pharmaceutical process data acquisition and traceability. Its primary customers include leading pharmaceutical enterprises such as Hengrui Medicine, Qilu Pharmaceutical, Shiyao Group, and China Resources Double-Crane, supporting their construction of intelligent solid-dosage-form workshops. Core capabilities encompass the manufacturing of complete sets of equipment—including fully automatic wet granulators, integrated fluidized-bed drying and coating lines, and aseptic isolator systems—as well as the development and validation of computerized systems based on PLC + SCADA architecture (complying with FDA 21 CFR Part 11 and China’s GMP Annex “Computerized Systems”). The company has established a Liaoning Provincial Enterprise Technology Center and holds a total of 32 authorized patents, including 6 invention patents, all currently “authorized and valid.”  

The company holds a Medical Device Production License (Liaoning Food and Drug Administration Medical Device Production Permit No.: 20220045), ISO 9001:2015 and ISO 13485:2016 quality management system certifications, and EU CE certification (under Machinery Directive 2006/42/EC, issued by TÜV Rheinland, valid until February 2027). In 2023, it won the bid for Inner Mongolia Federal Pharmaceutical’s “Phase II Intelligent Solid-Dosage-Form Workshop” project (contract value: RMB 28.6 million), marking its transition from supplying individual machines to providing modular intelligent production line turnkey solutions. Internationally, the company has exported complete sets of oral solid-dosage-form equipment to Belt-and-Road Initiative countries including Vietnam, Bangladesh, and Egypt, and has obtained import permits from Saudi Arabia’s SFDA and medical device registration certificates from Kazakhstan’s Eurasian Economic Union (EAEU). Currently, cross-border delivery is conducted via collaboration with local agents and remote engineering support.

Chemical equipment manufacturing

Automation Control and Instrumentation Systems

Engineering Design and Engineering Consulting

China

T - Technology and Patent Services

P - Equipment Procurement Services

S - On-Site Technical Upgrade Services

Dalian High-tech Zone Guangyuan Thermal Power Co., Ltd.

2001-07-30

Medium-sized

2

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Dalian High-tech Zone Guangyuan Thermal Power Co., Ltd., located in the Dalian High-tech Industrial Development Zone, Liaoning Province, is a regional centralized heating infrastructure operation enterprise approved by the Dalian High-tech Zone Administrative Committee and controlled by state-owned capital. Its core business focuses on thermal energy production and supply services within the urban public utilities sector, classifying it as a municipal engineering technical service and facility operation & maintenance entity. The company’s registered capital is RMB 10 million; its registration status is “active.” It serves approximately 2.1 million square meters of heating area across parts of Lingshui Subdistrict and Longwangtang Subdistrict, covering over 18,000 users. Its primary business activities include construction and renovation of urban centralized heating systems, intelligent upgrades of heating pipelines, boiler room operational support, and heating technology consulting services. Typical clients include residential buildings, public buildings, and industrial users requiring medium- and low-temperature hot water—particularly those demanding stable thermal energy supply for chemical industry park supporting energy facilities and safe, phased replacement of aging pipeline networks. Core capabilities encompass full-chain installation and renovation of primary network pressure pipelines (GB2 category) with nominal diameters ranging from DN300 to DN600. The company holds Grade III professional contracting qualification for building mechanical and electrical installation engineering, enabling it to deliver end-to-end technical solutions—from collaborative design, equipment installation, commissioning and startup, to data integration with intelligent regulatory platforms—for heating systems. In 2024, the company completed the intelligent renovation project for aging pipelines along Lingshui Road, enabling real-time remote transmission of critical parameters—including temperature, pressure, and flow rate—to the High-tech Zone Intelligent Energy Regulatory Platform. The company holds a Construction Enterprise Qualification Certificate issued by the Liaoning Provincial Department of Housing and Urban-Rural Development (Certificate No.: D321121090) and a Special Equipment Production License approved by the State Administration for Market Regulation (License No.: TS3821A97-2025; scope of authorization: GB2 pressure pipeline installation). Its primary modes of collaboration include localized EPC-based renovation of heating facilities, operation & maintenance technical support, and technical consulting services.

China

S - On-Site Technical Upgrade Services

Dalian Free Trade Zone Gaojia Chemical International Industry and Trade Co.,Ltd.

2001-04-12

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Dalian Gaojia Chemical Co., Ltd. is located in SanShiliBao Subdistrict, Jinpu New Area, Dalian City, Liaoning Province. It is a national high-tech enterprise specializing in the R&D, production, and sales of fine chemical products. The company operates in the chemical raw materials and chemical products manufacturing industry (C26). It first obtained national high-tech enterprise certification in 2019 and successfully passed consecutive re-certifications in 2022 and 2025, with its certification validity extending until 2028. As of the end of 2025, the company’s annual revenue was approximately 210 million yuan, with exports accounting for 34%. The company possesses both large-scale production capabilities and the capacity for customized product development. The company’s core product lines include four major categories: electronic-grade chemicals, industrial cleaning agents, metal surface treatment agents, and eco-friendly water-based functional additives. Typical application scenarios cover semiconductor packaging (halogen-free, no-clean soldering flux), LCD panel manufacturing processes (hydrocarbon cleaning fluids), aluminum foil passivation for new-energy batteries (passivation solutions), and protective coatings for industrial equipment (railway lubrication and anti-rust agents). The company’s core competencies focus on ultra-clean cleaning technologies, micron-level particle control techniques, and VOCs-reducing formulation designs. It holds three invention patents (including ZL202110427892.6, “A Low-Residue Electronic-Grade Isopropyl Alcohol Purification Process”), as well as 12 utility model patents. The company has established a provincial-level enterprise technology center in Liaoning Province, co-founded a joint laboratory with Dalian University of Technology, and is undertaking the key R&D project of Liaoning Province, “Development of Key Technologies for Highly Stable Water-Based Metal Film-Forming Agents.” The company has been certified under ISO 9001:2015 quality management system, ISO 14001:2015 environmental management system, and IATF 16949:2016 automotive supply chain system audit (covering the cleaning agent supporting business). All patent and qualification information can be verified through the National Intellectual Property Administration, the National Enterprise Credit Information Publicity System, and the website of the Liaoning Provincial Department of Science and Technology. Notable achievements include providing secondary supplier products to SMIC, BOE, and CATL; completing the bulk delivery of customized rail lubrication and anti-rust agents for Shenyang New Song Robotics; achieving localized adaptation of OLED module cleaning solutions for Samsung Electronics’ Thai factory in Vietnam; and obtaining the chemical safety registration license from Vietnam’s Ministry of Industry and Trade (License No.: DKHC-2025-0876). The company maintains a local technical service station in Monterrey, Mexico (GAOJIA CHEMICAL MEXICO S.A. DE C.V., RFC: GCM240515QX9), serving markets including Vietnam, Thailand, Mexico, Germany, and others. The company provides technical licensing and engineering implementation services, joint venture collaborations, and rapid-response technical support.

Fine Chemical Manufacturing

China

T - Technology and Patent Services

P - Equipment Procurement Services

Dalian Port Petrochemical Co.,Ltd.

2002-10-09

2

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Dalian Port Petrochemical Co., Ltd., located in Xigang District, Dalian City, Liaoning Province, is a modern enterprise specializing in port-based petrochemical logistics and energy storage & transportation services within the transportation support industry. Established jointly in 2004 by Liaoning Port Group Co., Ltd. and PetroChina Kunlun Energy Co., Ltd., the company has registered capital of RMB 1 billion and is recognized as a National Level-1 Enterprise for Dangerous Chemicals Safety Production Standardization and a Liaoning Provincial High-Tech Enterprise. Its core business encompasses storage, transshipment, loading/unloading, blending, bonded logistics, and value-added supply chain services for refined oil products and chemical commodities, providing deep support to sectors including petrochemicals, refining & petrochemical integration, biofuels, and bonded trade. Typical clients include global energy enterprises such as CNPC, Sinopec, CNOOC, Shell, BP, and Trafigura. The company operates a specialized petrochemical terminal cluster at the Dagushan Port Area, comprising one 50,000-DWT and one 300,000-DWT crude oil berth, plus seven refined oil and liquid chemical berths ranging from 50,000 to 100,000 DWT. Supporting these terminals are modern storage & transportation facilities with a total tank capacity exceeding 2 million cubic meters (including 800,000 cubic meters of bonded tank capacity), enabling full-category handling and storage of over 60 hazardous chemicals—including crude oil, fuel oil, gasoline, diesel, aviation kerosene, benzene, methanol, and ethylene glycol. The company has established a Liaoning Provincial Enterprise Technology Center and holds 23 authorized patents (including 7 invention patents). Key implemented projects include: “AI Vision-Based Real-Time Risk Early Warning System for Hazardous Chemicals Operations” (functionally verified by China Classification Society in 2024), LNG cold energy cascaded utilization, intelligent ship-shore joint inspection data exchange platform, and digital twin scheduling system for multimodal hazardous chemicals transportation. The company has obtained ISO 9001, ISO 14001, and ISO 45001 certifications and holds the “Port Operation License,” “Hazardous Chemicals Business License,” “Bonded Logistics Center (Type B) Registration Certificate,” and Customs AEO Advanced Certification. Representative projects include: completion in 2022 of China’s first port-level marine biofuel (HVO) blending and mixing center (annual processing capacity: 300,000 tons); execution since 2023 of regular bonded transshipment of Far East Russian crude oil via Dalian Port to refineries in the Yangtze River Delta region (annual transshipment volume exceeding 12 million tons); and launch in 2024 of the “Smart Customs Clearance Service Platform for Petrochemical Commodities,” reducing the end-to-end import process for hazardous chemicals to under four hours. International business operations primarily rely on collaborations with multinational freight forwarders, shipping lines, and energy traders; foreign trade throughput accounts for 58.3% of total throughput, serving markets in Japan, South Korea, Russia, Mongolia, and Southeast Asia, and integrating with the RCEP member countries’ automatic certificate-of-origin verification system.

Storage and Transportation Equipment and Tank Farm System

Supply Chain and Equipment Procurement Services

Operations

Maintenance

and Technical Services

China

S - On-Site Technical Upgrade Services

H - Human Resource Services

Dalian Port Design Research Institute Co.,Ltd.

1987-12-12

Medium-sized

2

0

0

Dalian Port Design and Research Institute Co., Ltd. (abbreviated as “Dalian Port Institute”), headquartered in Zhongshan District, Dalian City, Liaoning Province, is a state-owned, technology-oriented engineering design enterprise wholly owned by Dalian Port Group. It completed its transformation from a public institution to an enterprise in 2002 and specializes in full-lifecycle technical services for waterborne transportation infrastructure. Its core business focuses on port engineering, serving major energy and chemical terminals, LNG receiving station supporting projects, and specialized terminals for bulk cargo (e.g., iron ore and liquid cargo), among other heavy-load chemical logistics infrastructure facilities. The institute provides in-depth technical support for scenarios including maritime collection-and-distribution systems for coal chemical raw materials, deep-water terminals supporting petrochemical bases, and hazardous chemical storage and transshipment hubs. Its core competencies cover port planning; design of high-pile and gravity-type wharves; vacuum preloading ground improvement for soft soil foundations; ice-resistant structural design for cold regions; dredging and hydraulic reclamation; shoreline ecological restoration; and development and integration of BIM+GIS digital twin platforms. Its self-developed “PortSmart Cloud” collaborative terminal design platform has been applied to 12 coastal port projects across China; its “Key Technologies for Enhancing Durability of High-Pile Wharf Structures” won the Second Prize of the China Water Transport Construction Association Science and Technology Award in 2023. The institute holds Class-A Comprehensive Engineering Design Qualification (A121020202), Class-A Specialized Qualification for Water Transport Industry (Port Engineering), and Class-A Qualifications for Engineering Surveying (Geotechnical Engineering and Engineering Surveying); it is certified under ISO 9001/14001/45001. Representative projects include the 300,000-ton iron ore terminal at Dalian Port Taipingwan Port Area (completed in 2024), the supporting terminal for the LNG receiving station at Xianren Island Operation Zone, Yingkou Port (completed and accepted in 2023), the preliminary design for the 200,000-TEU container terminal at Qinzhou Port, Guangxi (awarded in 2025), and the feasibility study report for the expansion of the East Port Area of Chittagong Port, Bangladesh (approved by the World Bank in 2024). Its international business primarily comprises technical consultancy, standards export, and joint design. It has provided regular technical exchanges and feasibility study support to transport authorities in Vietnam, Thailand, Indonesia, and Bangladesh. Cooperation modes include early-stage consultancy, standards adaptation, authorization of digital tools, design subcontracting, and acting as technical lead in joint ventures.

China

T - Technology and Patent Services

E - Engineering Design Services

Dalian Fusheng Pharmaceutical Co., Ltd.

2003-01-22

Small

2

0

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Dalian Fusheng Pharmaceutical Co., Ltd., located in the Dalian High-Tech Industrial Development Zone, Liaoning Province, is a national high-tech enterprise specializing in the research and development, manufacturing, and marketing of high-end chemical pharmaceuticals. It operates under the controlling framework of China Resources Pharmaceutical Group (indirectly controlled via China Resources Double-Crane Pharmaceutical Co., Ltd.) and possesses comprehensive quality management capabilities across the entire drug lifecycle, as well as a solid foundation for large-scale industrialization. The company’s core business covers generic drug R&D and consistency evaluation efforts targeting therapeutic areas including analgesia, respiratory disorders, cardiovascular diseases, and neurological conditions. Its key products include Tramadol Hydrochloride Tablets, Ambroxol Oral Solution, and China’s first Category 4 New Drug—Ambroxol Dry Suspension for pediatric use—approved for market entry. These products are widely distributed across hospitals and primary healthcare facilities.  

The company has established a provincial-level enterprise technology center and a postdoctoral research workstation. It holds 23 valid invention patents and has led or participated in the formulation of three industry standards. Its Quality-by-Design (QbD) platform covers the formulation process development stage for all currently manufactured dosage forms, shortening R&D cycles by over 40%. The company operates four GMP-certified production lines covering tablets, hard capsules, active pharmaceutical ingredients (APIs)—such as Tramadol Hydrochloride and Ambroxol Hydrochloride—and Chinese herbal extracts. Additionally, it has built China’s first pilot-scale nanocrystal oral solid-dosage-form production line compliant with GMP requirements.  

The company has obtained certifications for three major management systems: ISO 9001:2015, ISO 14001:2015, and ISO 45001:2018. Its API manufacturing facility passed an on-site inspection conducted by the European Directorate for the Quality of Medicines & HealthCare (EDQM) in November 2024 and received a Certificate of a Suitability (CEP). In February 2025, it obtained formal confirmation from the U.S. Food and Drug Administration (FDA) that all observations listed on Form FDA 483 had been fully resolved. Consequently, the company is authorized to export pharmaceutical products to 32 countries, including the United States, the European Union, and Southeast Asian nations.  

Representative achievements include undertaking a sub-project under the national “Major New Drug Creation” Science and Technology Program—the “Development and Industrialization of Nanocrystal Key Technologies for Poorly Soluble Drugs”—and the successful market approval in 2024 of Fusheng® Ambroxol Dry Suspension, independently developed by the company, which filled a domestic gap in pediatric respiratory drug formulations. In 2025, API export revenue reached USD 42.8 million, representing a 19.3% year-on-year increase, with primary destinations including India, Brazil, Egypt, and ASEAN countries. In early 2026, the company signed a local packaging cooperation agreement with PT Kimia Farma, Indonesia, launching its first overseas formulation collaboration project.

Pharmaceuticals and Chemical Intermediates

Fine Chemical Manufacturing

Chemical Engineering Technology Research and Development and Process Package

China

T - Technology and Patent Services

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